Vilnius Picture Gallery is situated in the former Chodkeviciai Palace built in the early 17th century. The Palace has constantly been expanded and reconstructed. In the 19th century it became a characteristic building of the late classicism style. At present it is one of the most interesting ensembles of this style in Vilnius.
Many elements of interior decoration (stoves, wall sculptures) characteristic of that period have been retained in the halls of the first floor with the recreated interior of the 19th century inside. As it was usual for Lithuanian mansions, collections of medals, portrait miniatures, views of the old Vilnius, portraits of well-known townsmen (collection of Vilnius Philanthropy Society) are exhibited in the halls of the gallery.